RegenBell 2024 symposium on Stem Cells and Regenerative Medicine

Institut d’Estudis Catalans (IEC), C/ del Carme, 47 08001 Barcelona

THURSDAY, NOVEMBER 21

9:00

Registration

9:30

Welcome
Gabriel Capellá, General Director of Bellvitge Biomedical Research Institute (IDIBELL)

9:40

SESSION I: Development and regeneration of definitive endoderm
Chairs: Meritxell Rovira, IDIBELL, P-CMR[C] and UB, L’Hospitalet de Llobregat
& Esteban Hoijman IDIBELL and CSIC, l’Hospitalet de Llobregat

9:45

Modeling pancreas development and disease with organoids
Anne Grapin-Botton, Max Planck Institute for Cell Biology and Genetics, Dresden

10:15

Mucosal macrophages govern intestinal regeneration in response to radiation injury
Jordi Guiu, IDIBELL and P-CMR[C], L’Hospitalet de Llobregat

10:45

Selected short talks:

Simona Chera, University of Bergen

Mapping Global Regulators of Islet Regeneration Programs

Joffrey Pelletier, IDIBELL, UB and IRB Barcelona

The nucleolus connects inflammation and tumor cell plasticity in colorectal cancer.

11:05

Coffee break

11:45

SESSION II: Stem cell regeneration in aging and disease
Chairs: M. Carolina Florian, ICREA, IDIBELL and P-CMR[C], L’Hospitalet de Llobregat
& Alessandra Giorgetti, IDIBELL, P-CMR[C] and UB, L’Hospitalet de Llobregat

11:50

Mechanistic insights into stem cells in aging and regeneration
Hartmut Geiger, Ulm University, Ulm

12:20

Impact of germline GATA2 mutations: from functional deficiency to development of myeloid neoplasms
Laëtitia Largeaud, Toulouse University, Tolouse

12:50

Selected short talks:

Patricia Herrero Molinero, Hospital del Mar Research Institute

Notch signaling modulates the quiescent state in hematopoietic stem cells during fetal development

Joan Pera, IDIBELL and P-CMR[C]

Unraveling Myeloid disease progression: Impact of SETBP1 and ASXL1 mutations in GATA2 deficiency

13:15

LUNCH & posters

15:15

SESSION III: iPSC for disease modeling
Chair: Anna Veiga , IDIBELL and P-CMR[C], L’Hospitalet de Llobregat

15:20

Human organoid models to understand selective neural vulnerability in neurodegenerative diseases
Natalia Rodríguez Muela, German Center for Neurodegenerative Disease, Dresden

15:50

Culture-acquired genetic variation in human pluripotent stem cells: the causes and consequences
Ivana Barbaric, Centre for Stem Cell Biology, University of Sheffield, Sheffield

16:20

Selected short talks:

Valentina Baruffi, IDIBELL and UB

Modelling neuro-immune interaction in Parkinson’s disease using an iPSC-based autologous in vitro system

Alberto Ortega, IDIBELL and UB

Harnessing Developmentally Programmed Extracellular Matrices to Improved the fidelity of iPSC-derived

16:40

Coffee break

17:20

SESSION IV: Manipulating collective cell behaviour
Chair: Jordi Guiu , IDIBELL and P-CMR[C], L’Hospitalet de Llobregat

17:25

Geometry-driven fetal to adult transition in the intestine
Martti Maimets, The Novo Nordisk Foundation Center for Stem Cell Medicine (reNEW), Copenhagen

17:55

Building barriers: developing in vitro 3D brain microvascular models to study malaria pathogenesis
Maria Bernabeu, EMBL, Barcelona

18:15

Poster session

20:00

End of the session

FRIDAY, NOVEMBER 22

9:00

SESSION V: Restoration of homeostasis and tissue repair
Chair: Mireya Plass, IDIBELL and P-CMR[C], L’Hospitalet de Llobregat

9:05

Lifelong epigenetic effects of maternal diet in metabolic liver disease in progeny

Salvador Aznar Benitah, ICREA and IRB Barcelona, Barcelona

9:35

Dynamics of epithelial protection in the live embryo
Esteban Hoijman, IDIBELL and CSIC, l’Hospitalet de Llobregat

10:05

Selected short talks:

Carlos Sebastián, UB and IBUB

Metabolism in the driver seat: Pdk1+ epithelial cells link stem cell activity and tumorigenesis in the intestine

Joshua Frenster, UPF

Gastruloids as a model for pre-gastrulation Cell Competition in Mammals

10:25

Coffee break

11:05

SESSION VI: Keynote talk
Chair: Angel Raya, ICREA, IDIBELL and P-CMR[C], L’Hospitalet de Llobregat

11:10

Adult heart regeneration in zebrafish, and genetic compensation
KEYNOTE SPEAKER: Didier Stainier, Director and Scientific Member at the Max Planck Institute for Heart and Lung Research, Bad Nauheim

12:10

Poster/short talk award and concluding remarks
Angel Raya, ICREA, IDIBELL and P-CMR[C], L’Hospitalet de Llobregat

13:00

End of the conference

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